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Alcott Chromatography

When GP Instruments was looking for acquisition candidates we wanted to find a company that had a good reputation, useful technology and was known in the marketplace. Alcott Chromatography fit these requirements. We were happy to be able to acquire Alcott Chromatography from Micromeritics, Inc in the Spring of 2008.

Alcott Autosamplers are workhorses in the laboratory with some of our customers using them around the clock. Our basic design is available in many configurations depending on your needs but all of those configurations are based on two basic approaches to autosampling.

Our Model 709 variation is based on a positive displacement approach to getting samples from your vial to your instrument. The basics of how positive displacement with in vial filtering works are illustrated in a video we put together, You can see it here. Positive displacement involves no syringes, works with various viscosities and can include the in-vial filtering step. How in-vial filtering compares to hand filtering and how viscosity can effect the autosampler can be found in these application briefs:

  • Nitroglycerin Tablet Assy Comparison
  • Hypertensive Drug Assay Comparison
  • Sample Viscosity Effects
  • Comparison of In-Vial Filter with Disposable Syringe Filter Disks


      • Our Model 719 is based on using a precision syringe to draw sample from the vial and send it to your instrument. The use of a syringe allows us to add additional steps to a procedure so that we can provide rinse, reconsititution, and dilution. When properly configured the Model 719 will provide the lowest carry over between injections. This is a must for LC/MS. Data supporting this claim can be seen in these presentations:

      • Sample Carryover Reduction
      • Model 719 Compared to Competitors Autosampler
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